M Bishr Omary Selected Research

K-18 conjugate (K18)

1/2016	Keratins: Biomarkers and modulators of apoptotic and necrotic cell death in the liver.
12/2015	Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice.
9/2015	Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation.
8/2015	Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury.
7/2015	Absence of keratins 8 and 18 in rodent epithelial cell lines associates with keratin gene mutation and DNA methylation: Cell line selective effects on cell invasion.
11/2013	CD73 (ecto-5'-nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory-denk body formation.
1/2012	Non-coding keratin variants associate with liver fibrosis progression in patients with hemochromatosis.
1/2011	Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation.
9/2010	Cytoskeletal keratin glycosylation protects epithelial tissue from injury.
9/2010	Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations.

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M Bishr Omary Research Topics

Disease

33	Liver Diseases (Liver Disease) 01/2018 - 02/2002
13	Fibrosis (Cirrhosis) 01/2019 - 05/2003
9	Porphyrias (Porphyria) 01/2021 - 04/2010
8	Neoplasms (Cancer) 10/2019 - 09/2003
8	Pancreatitis 01/2018 - 10/2004
7	End Stage Liver Disease 01/2019 - 09/2005
6	Acute Liver Failure (Fulminant Hepatic Failure) 01/2016 - 09/2010
6	Chronic Hepatitis C 01/2012 - 06/2006
5	Fatty Liver 01/2018 - 11/2003
5	Non-alcoholic Fatty Liver Disease 01/2018 - 11/2013
5	Colitis 06/2015 - 03/2004
5	Inflammation (Inflammations) 12/2014 - 03/2004
5	Infections 01/2012 - 08/2004
4	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 08/2003
4	Liver Cirrhosis (Hepatic Cirrhosis) 11/2017 - 05/2003
3	Laminopathies 01/2020 - 07/2013
3	Liver Failure 01/2019 - 01/2013
3	Hypoxia (Hypoxemia) 01/2018 - 10/2012
3	Necrosis 01/2016 - 01/2013
3	Disease Progression 08/2009 - 05/2005
2	Rare Diseases (Rare Disease) 01/2021 - 01/2020
2	Virus Diseases (Viral Diseases) 01/2016 - 09/2005
2	Erythropoietic Protoporphyria 09/2015 - 07/2012
2	Skin Diseases (Skin Disease) 08/2015 - 07/2003
2	Chemical and Drug Induced Liver Injury 08/2015 - 05/2003
2	Starvation 06/2015 - 06/2006
2	Neoplasm Metastasis (Metastasis) 02/2015 - 09/2003
2	Hepatitis C 11/2013 - 10/2011
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2012 - 08/2009
2	Hyperplasia 01/2011 - 03/2004
2	Chronic Pancreatitis 04/2008 - 05/2006
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2007 - 05/2006
2	Barrett Esophagus (Barrett's Esophagus) 06/2007 - 09/2006
2	Adenocarcinoma 06/2007 - 09/2006
1	Systemic Mastocytosis 12/2022
1	Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara) 12/2022
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2022
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2021
1	Erythropoietic Porphyria (Congenital Erythropoietic Porphyria) 01/2021
1	Liver Neoplasms (Liver Cancer) 01/2019
1	Lipodystrophy 01/2018
1	Chronic Disease (Chronic Diseases) 01/2018

Drug/Important Bio-Agent (IBA)

42	Keratins (Keratin)IBA 12/2022 - 02/2002
23	K-18 conjugate (K18)IBA 01/2016 - 05/2003
14	Proteins (Proteins, Gene)FDA Link 10/2019 - 05/2003
10	Keratin-8 (Keratin 8)IBA 12/2015 - 05/2003
6	Phosphotransferases (Kinase)IBA 12/2022 - 03/2002
6	PorphyrinsIBA 01/2021 - 09/2015
5	Heme (Haem)IBA 01/2021 - 01/2016
5	LaminsIBA 01/2018 - 07/2013
4	AntibodiesIBA 10/2019 - 08/2003
4	EnzymesIBA 01/2019 - 11/2005
4	CeruletideIBA 01/2018 - 10/2004
4	Keratin-18 (Keratin 18)IBA 12/2015 - 08/2003
4	Acetaminophen (Paracetamol)FDA LinkGeneric 09/2015 - 09/2010
4	DNA (Deoxyribonucleic Acid)IBA 09/2006 - 05/2003
3	Lamin Type A (Lamin A)IBA 01/2020 - 06/2017
3	protoporphyrin IXIBA 01/2019 - 09/2015
3	NF-kappa B (NF-kB)IBA 01/2018 - 10/2004
3	Transcription Factors (Transcription Factor)IBA 01/2018 - 10/2012
3	CaspasesIBA 01/2016 - 04/2011
3	LipidsIBA 01/2016 - 09/2003
3	Intermediate Filament ProteinsIBA 12/2015 - 03/2005
3	Pharmaceutical PreparationsIBA 10/2015 - 04/2006
3	Messenger RNA (mRNA)IBA 11/2013 - 10/2004
3	Hemin (Panhematin)FDA Link 05/2011 - 11/2005
2	5'-Nucleotidase (5' Nucleotidase)IBA 10/2019 - 12/2014
2	Adenosine (Adenocard)FDA LinkGeneric 10/2019 - 11/2013
2	Deferoxamine (Desferal)FDA LinkGeneric 01/2019 - 09/2015
2	CateninsIBA 01/2019 - 06/2013
2	Ethanol (Ethyl Alcohol)IBA 01/2018 - 10/2012
2	Oxygen (Dioxygen)IBA 01/2018 - 10/2012
2	BuffersIBA 11/2017 - 07/2013
2	Choline (Choline Chloride)IBA 01/2017 - 11/2005
2	EpitopesIBA 01/2016 - 02/2006
2	AcidsIBA 09/2015 - 06/2007
2	Biological ProductsIBA 02/2015 - 09/2006
2	UbiquitinIBA 11/2013 - 09/2008
2	sphingosine phosphorylcholineIBA 05/2012 - 09/2003
2	Amino Acids FDA Link 01/2012 - 05/2006
2	Alanine Transaminase (SGPT)IBA 10/2011 - 04/2011
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2011 - 05/2005
2	Heme Oxygenase-1IBA 01/2011 - 11/2005
1	midostaurinIBA 12/2022
1	Uroporphyrinogen III Synthetase (Uroporphyrinogen-III Synthase)IBA 01/2021
1	coproporphyrin IIBA 01/2021
1	Acitretin FDA Link 01/2021
1	Polysaccharides (Glycans)IBA 10/2019
1	Glycoproteins (Glycoprotein)IBA 10/2019
1	Purinergic P1 Receptor AgonistsIBA 10/2019
1	Aminolevulinic Acid (Levulan)FDA Link 01/2019
1	3,5- diethoxycarbonyl- 1,4- dihydrocollidineIBA 01/2019
1	3,3,5,5-tetramethyl-1-pyrroline N-oxide (TMPO)IBA 01/2018
1	CytokinesIBA 01/2018
1	LigandsIBA 01/2018
1	Fibrinogen (Factor I)FDA Link 01/2018

Therapy/Procedure

4	Therapeutics 12/2022 - 05/2005
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2021
1	Immunotherapy 10/2019
1	Hepatectomy 01/2018